Fusarium wilt of cotton, which is caused by Fusarium oxysporum f.sp vasinfectum (Fov) is a relatively new disease in Australia. The devastating nature of the disease and the lack of effective control measures are causing serious concern in the industry. There are now only four Australian cotton-growing areas that have not yet recorded the disease. The Australian Cotton Industry is making a concerted effort to minimise further spread of Fov. The different measures include keeping farm machinery and vehicles free from crop debris and soil, retaining irrigation run-off water on the farm and avoiding spillage of cotton during transport from the farm the processing facility. Any stress on the plant, for example water logging, appear to exacerbate the disease. There are no cotton varieties in Australia with complete resistance to Fusarium wilt. The varieties are usually divided into three susceptibility groups- least, moderately and most susceptible. Even the least susceptible varieties appear to be very susceptible in the seedling stage. The current recommendations for managing the disease include using the least susceptible varieties, retention of crop residues on the surface for as long as possible after harvest, increased seed rate by up to 30%, control of weeds that host the pathogen and farm hygiene. The use of bio control agents is another tactic that can be included in this package.